General Malignancy Checklist
Categorize the malignancy
- Where the malignancy originated
- If it is a primary tumor
- If it is a recurrent tumor
NOTE: If the primary site cannot be identified, SSA uses the evidence documenting the site(s) of metastasis to evaluate the malignancy under Listing 13.27.
Clarify extent of involvement of the malignancy
- Have the treating source clarify tumor stage if it isn’t clear
- If it is locally advanced
- If it is metastatic
- Local metastasis - tumors that have metastasized to regional tissue or regional lymph nodes
- Distant metastasis - tumors that have metastasized beyond the regional lymph nodes
NOTE: Malignancies that have distant metastases usually meet a listing, with the exception of the following tumors:
- Testicular tumors
- Well-differentiated thyroid carcinoma
- Prostate adenocarcinoma with bone metastasis
- Hodgkin’s lymphoma
These exceptions require at least three months of longitudinal records to decide whether the intended treatment is effective.

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